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Ciclospray

$13.75 USD
Vaccines
Per pill
In Stock
Ciclesonide is a glucocorticoid used to treat obstructive airway diseases. It is marketed under the brand name Alvesco for asthma and Omnaris/Omniair for hayfever in the US & Canada. Phase 3 trials for the hayfever indication outside the US are ongoing.
8.95$. Delivery period 14-21 days.
Free for orders more than $200.00 USD
27.95$. Delivery period 5-7 days.
Free for orders more than $300.00 USD

Ciclospray 50 mcg

Name Quantity Price Each Total Price Save
Ciclospray 50 mcg 1 pills $22.00 USD $22.00 USD
Ciclospray 50 mcg 2 bottles $20.90 USD $41.80 USD
+ Bonus - 3 pills
$2.20 USD
Ciclospray 50 mcg 3 bottles $19.86 USD $59.58 USD
+ Bonus - 3 pills
$6.42 USD
Ciclospray 50 mcg 4 bottles $18.86 USD $75.44 USD
+ Bonus - 6 pills
$12.56 USD
Ciclospray 50 mcg 5 bottles $16.98 USD $84.90 USD
+ Bonus - 6 pills
$25.10 USD
Ciclospray 50 mcg 6 bottles $15.28 USD $91.68 USD
+ Bonus - 6 pills
$40.32 USD
Ciclospray 50 mcg 10 bottles $13.75 USD $137.50 USD
+ Bonus - 12 pills
$82.50 USD
  • Product overview

Ciclesonide is a glucocorticoid used to treat obstructive airway diseases. It is marketed under the brand name Alvesco for asthma and Omnaris/Omniair for hayfever in the US & Canada. Phase 3 trials for the hayfever indication outside the US are ongoing.

Pharmacokinetics

Absorption
Prodrug converted to active metabolite, des-ciclesonide, after topical administration. Negligible serum concentrations following intranasal administration. Des-ciclesonide C max below 30 pg/mL.

Distribution
Following IV administration, Vd of ciclesonide and des-ciclesonide are approximately 2.9 and 12.1 L/kg, respectively, and protein binding averages at least 99% for ciclesonide and its metabolite.

Metabolism
Des-ciclesonide is metabolized in the liver by the CYP3A4 isozyme and, to a lesser degree, CYP2D6.

Elimination
After IV administration, predominantly excreted in the feces (66%) and approximately 20% or less in the urine.

Special Populations
Hepatic Function Impairment. When administered by oral inhalation, dosage adjustments are not needed in patients with hepatic function impairment.

Ciclesonide Adverse Reactions / Ciclesonide Side Effects

CNS
Headache (7%).

EENT
Nasopharyngitis (7%); epistaxis (5%); pharyngolaryngeal pain (3%); ear pain (2%).

Precautions

Monitor
Closely monitor patients with a change in vision and with a history of glaucoma or cataracts.

Other Drug Interactions

Ketoconazole
May increase des-ciclesonide exposure by about 3.6-fold. Coadminister with caution.

Other Interactions

Information Not Available

Dosage

Perennial Allergic Rhinitis Adults and Children 12 years of age and older.
Nasal inhalation 200 mcg/day administered as 2 sprays (50 mcg/spray) in each nostril once daily (max, 200 mcg/day).


Seasonal Allergic Rhinitis Adults and Children 6 years of age and older.
Nasal inhalation 200 mcg/day administered as 2 sprays (50 mcg/spray) in each nostril once daily (max, 200 mcg/day).

List of Contraindications

Ciclesonide and Pregnancy

Caution when used during pregnancy

Ciclesonide and Lactation

Caution when used during lactation

Ciclesonide and Other Contraindications

Standard considerations

Storage

Store at 59° to 86°F. Do not freeze